ABSTRACT
There are many causes of thrombocytopenia. These causes may be either pathologic or non-pathologic such as platelet activation during blood collection, undercounting of megatrombocytes, in vitro agglutination of platelets due to EDTA, monoclonal antibodies that bind to platelet glycoprotein receptors. Differential diagnosis which is performed fast might prevent both mis- and delayed diagnosis about emergency owing to thrombocytopenia and unnecessary diagnostic tests and treatment with excluding pseudothrombocytopenia which is the most frequent cause of thrombocytopenia. Herein, we presented pseudothrombocytopenia due to EDTA in a child with Ewing sarcoma.