ABSTRACT

Although elevated serum IgE is acceptedasasignofatopy, high total IgE level may accompany with non-allergic asthma and contribute to pathogenesis and severity of the disease independently from atopy. İn this case report, we present a patient of us whose allergy skin tests and specific IgEs were negative, who was started omalizumab treatment following obtaining weak positivity against Dermatofagoides pteronysinus in intradermal tests repetaed with one year interval and who significantly benefited from treatment.

Keywords: Asthma; Omalizumab; İmmunoglobulin E, non allergy