Association of complete blood count parameters with liver histology and atherosclerosis in non-alcoholic fatty liver disease
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Original Article
P: 71-77
September 2018

Association of complete blood count parameters with liver histology and atherosclerosis in non-alcoholic fatty liver disease

Gulhane Med J 2018;60(3):71-77
1. University of Health Sciences, Gülhane Faculty of Medicine, Department of Gastroenterology, Ankara, Turkey
2. University of Health Sciences, Gülhane Faculty of Medicine, Department of Internal Medicine, Ankara, Turkey
3. University of Health Sciences, Gülhane Faculty of Medicine, Department of Radiology, Ankara, Turkey
No information available.
No information available
Received Date: 19.03.2018
Accepted Date: 14.04.2018
Publish Date: 15.09.2018
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ABSTRACT

Aims:

We aimed to evaluate the relationship between complete blood count parameters, liver histology and atherosclerosis parameters in patients with non-alcoholic fatty liver disease (NAFLD).

Methods:

We included the data of biopsy-proven 66 nonalcoholic steatohepatitis, 34 simple steatosis patients and 49 healthy controls to the study. Metabolic syndrome parameters data collected from all participants. Carotid intima media thickness, flow mediated dilatation, pulse wave velocity (PWV) were measured for atherosclerosis.

Results:

There was no significant difference among groups in terms of red blood cell distribution width, mean platelet volume, and neutrophil to lymphocyte ratio parameters. Hemoglobin levels in control subjects were lower than NAFLD subgroups, but no significant difference was found between NAFLD subgroups. In correlation analysis, there was only positive association between hemoglobin and PWV.

Conclusions:

High hemoglobin concentration may represent an increased risk of the development of NAFLD.