ABSTRACT
Systemic contact dermatitis is a delayed hypersensitivity reaction in the skin after systemic exposure to an allergen that individuals who have been sensitized before by topically. Paraphenylendiamine (PPD) is a substance which is used frequently in temporary henna tattos and hair dyes that popular particularly among young people in recent years. Our case had a medical history of a contact dermatitis development after the application of temporary henna tatto containing PPD and had a flare of previous eczematous dermatitis after contact with PPD again. We present our case because of the much less occurance of systemic contact dermatits than the other dermatitis and to emphasize that PPD may take part in the etiology of systemic contact dermatitis.