ABSTRACT

Castleman’s disease is a benign and rare disease developing in lymph nodes. İt is characterized by B-cell hyperproliferation and B-cells produce interleukin-6. This disease has two types; multicentric type often presents with fever, hepatomegaly, splenomegaly or lymphadenopathy, whereas unicentric type is diagnosed occasionally. Multicentric type is treated with combination chemotherapy regimens and unicentric type is treated with surgery and/or radiotherapy.

İn this article, a 29-year-old male patient with unicentric type, hyalen vascular Castleman’s disease with local recurrence after surgery and treated with radiotherapy is presented with management and related literatüre review.