ABSTRACT

The placental site trophoblastic tumours of uterus is a rare form of gestational trophoblastic disease. In literature 90 placental site trophoblastic tumours of which %20 are malign were documented. Although 19 years have passed from the description of trophoblastic tumours, the diffuculties about the diagnosis, treatment and the biological behaviour have been going on. Unexplained vaginal bleeding, amenorrhea and persistant low hCG levels should remind us the PSTT. It may occur weeks or months after term pregnancy, spontaneous or terapotic abortion or termination of the molar pregnancy. Although the average age of the disease is 28, it should not be forgotten that it can be seen in all age groups also including postmenoposal period.

To determine the prognosis there is still no histological, immunohistochemical and chromosomal diagnose method. Since tumour is insensitive to condensed and aggressive chemoteraphy, metastasis is the indicator of low prognosis.

PSTT cases in which the biological behaviour cannot be predicted before, since a poor response is obtained by chemoteraphy and radioteraphy, surgical treatment (TAH+BSO) is still the best choice of treatment which is both curative and gives a chance to the long time survival.