ABSTRACT
Intracranial lipomas are very rare tumors with an incidence of approximately 0.1% of diagnosed brain tumors and 0.08% of tumors found on autopsy. Lipomas, classified in conjenital malformations of the central nervous system, constitute 0.06-0.46% of intracranial lesions. These tumors are usually asymptomatic, and detected during radiological investigations and autopsy. Intracranial lipomas usually present with headache, epileptic seizures, psychomotor retardation and cranial nerve paralysis. A 20-yearold male patient admitted to our department because of headache. He had the diagnosis of epilepsy (under control) since 12-year-old. His neurologic examination and neurophysiologic investigations were normal. His brain magnetic resonance imaging demonstrated a 5.5x6x8 cm sized interhemispheric mass lesion in fat intensity in all secanses and callosal agenesis. This article was presented to emphasize the co-existence of intracranial lipoma, callosal agenesis and epilepsy in the light of similar cases in the literature.