ABSTRACT

It is known that cytomegalic inclusion disease due to congenital CMV infection almost always occurs after a primary infection of the mother during her pregnancy who has not preconceptual immunity, and screening tests mainly aim to identify these primary infections. However, it has been reported that there are no significant differences in the incidence of cytomegalic inclusion disease, clinical presentation of the disease and rate of long-term sequela occuring after primary or recurrent maternal infection. By presenting cytomegalic inclusion disease which developed in the newborn of a mother with preconceptual immunity in this article, we aimed to emphasize that recurrent maternal CMV infection may result in serious problems on the contrary to the common knowledge. Additionally we aimed to point out the necessity of making screening tests in a manner to identify maternal primary as well as recurent infections in countries like ours in where seroprevalence of CMV approaches to 100% in early ages.

Keywords: CMV infection, congenital, recurrent