Original Article

An epidemiological overview of anti-hbc total test positivity in blood banking practice

10.5455/gulhane.174101

  • Soner Yılmaz
  • Sebahattin Yilmaz
  • Rıza Aytaç Çetinkaya
  • Türker Türker
  • İsmail Yasar Avcı
  • Bulent Ahmet Beşirbellioğlu
  • Can Polat Eyigün

Received Date: 08.10.2014 Accepted Date: 05.05.2015 Gulhane Med J 2016;58(2):174-176

Hepatit B Virus (HBV) infection is a serious global health problem with a broad clinical spectrum. This study aims to assess the rates of the HBV exposure with the results of anti-HBc tests in healthy blood donors within demographic data. A total of 5148 people were included to the study, who applied to Regional Blood Center of Gulhane Military Faculty of Medicine (GMMF) between January 2013 and June 2013. The number of males and females were 4982 (97.1%) and 145(2.9%), respectively. Mean age was 27.54±9.36. Blood samples of the donors were tested for anti-HBc plus HBsAg tests with microparticule enzyme immunoassay (Architect i2000 SR, Abbott® ) before the donation. Donors whose anti-HBc test results were positive information of gender, age and place of birth were noted, retrospectively. Among 5148 donors, 21 (0.4%) were positive for HBsAg, while the remaining 515 of 5127 (10.4%) were positive for anti-HBc. Among the donors whose the place of birth from Southeast and East Anatolian regions anti-HBc positivity rate was found as 16.5%, those in other regions the results were yielded 9.2%. The difference between two groups was statistically significant (p<0.001). The test results of anti-Hbc in 18-25 and 26-63 years old groups was found 6.1% and 16%, respectively. The difference between these two groups was statistically significant (p<0.001). The results can be interpreted as mass vaccination and preventive medicine practices have not resulted at the desired level for these region.

Keywords: Hepatitis B Virus, Hepatitis B core antibodies, blood donors