This study was performed at GATA Haydarpaşa Training Hospital, Underwater and Hyperbaric Medicine Service between the years 1997 and 2000. We searched therapeutic efficiency of Hyperbaric oxygen Therapy (HBO2) by measuring Transcutaneous partial oxygen and CO2 pressures (TcPO2 and TcPCO2) in patients who had wounds caused by diabetes Mellitus. There were 50 cases in our study. Thirty of them were the study group who had been treated with HBO2 and twenty of them were the control group who had been treated with therapeutic regimens without HBO2.

TcPO2 and TcPCO2 measurements of the therapy group were made at the begining, 15th session and 30th session of therapy. We detected a significant increase at TcPO2 when we compared the results (p < 0.05). There were no significant difference for TcPCO2 between pre-therapy and 15th session measurements (p > 0.05). By the way, a significant decrease was found between pre-therapy and 30th session, and also 15th session and 30th session (p <0.05). We didn't fınd a significant increase in TcPO2 values in major amputation and no change subgroups (p>0.05). We found a significant increase in TcPO2 values in minor amputation and succesfully treated group after therapy (p < 0.05).

TcPO2 and TcPCO2 measurements were important in diagnostic and therapeutic features of wounds due to diabetes and periferic vascular insufficiency.

Keywords: Hyperaric Oxygen Therapy, Diabetic Foot, Transcutaneous Partial Oxygen Pressure