Case Report

Can anti IgE treatment be used in non-atopic asthma patients; thoughts of a case about the role of IgE in asthma


  • Ali Kutlu
  • Ersin Demirer
  • Sami Ozturk
  • Ali Gunes
  • Ozgur Kartal
  • Ogün Sezer
  • Zafer Kartaloglu

Received Date: 07.10.2011 Accepted Date: 14.12.2011 Gulhane Med J 2014;56(1):42-44

Although elevated serum IgE is acceptedasasignofatopy, high total IgE level may accompany with non-allergic asthma and contribute to pathogenesis and severity of the disease independently from atopy. İn this case report, we present a patient of us whose allergy skin tests and specific IgEs were negative, who was started omalizumab treatment following obtaining weak positivity against Dermatofagoides pteronysinus in intradermal tests repetaed with one year interval and who significantly benefited from treatment.

Keywords: Asthma; Omalizumab; İmmunoglobulin E, non allergy