GULHANE MEDICAL JOURNAL 2004 , Vol 46 , Issue 3
Acute Renal Allograft dysfunction Due to Acute Pyelonephritis
Dr. Ali AVCI1, Dr. Yusuf OĞUZ2, Dr. İ. Yaşar ÖZGÖK3, Dr. Selahattin BEDİR3, Dr. Müjdat YENİCESU2, Dr. Abdülgaffar VURAL2, Dr. Ömer GÜNHAN4
1Mevki Asker Hastanesi, Üroloji Servisi
2Gülhane Askeri Tıp Akademisi, Nefroloji BD.
3Gülhane Askeri Tıp Akademisi, Üroloji ABD.
4Gülhane Askeri Tıp Akademisi, Patoloji ABD.
Purpose: The most common causes of allograft dysfunction in the early posttransplantation period include acute rejection, drug toxicity (cyclosporine toxicity), acute tubular necrosis, reperfusion injury, urinary tract/vascular obstruction, surgical complications and infections. The clinical manifestations of these processes are nonspesific and occasionally allograft dysfunction may be multifactorial. It has been reported that urinary tract infection (UTI) may also lead to renal allograft dysfunction due to acute pyelonephritis in these patients. Renal biopsy therefore is frequently used to diagnose the specific cause of acute graft dysfunction.

We report two cases with acute allograft failure due to acute pyelonephritis, which were confirmed by graft biopsies. In both cases, after appropriate antimicrobial therapy, allograft functions recovered. Keywords : Acute Renal Failure, Kidney Transplant, Acute Pyelonephritis