GULHANE MEDICAL JOURNAL 2019 , Vol 61 , Issue 2
Evaluation of the central corneal thickness, retinal thickness and intraocular pressure in patients with euthyroid Hashimoto's thyroiditis
Fatma Neslihan Cuhacı Seyrek1,Hüsniye Başer1,Nagihan Uğurlu2,Fatma Yülek2,Reyhan Ersoy1,Nurullah Çağıl2,Bekir Çakır1
1Ankara Yildirim Beyazit University, Faculty of Medicine, Endocrinology and Metabolism, Ankara, Turkey
2Ankara Yildirim Beyazit University, Faculty of Medicine, Ophthalmology, Ankara, Turkey
DOI : 10.26657/gulhane.00052 Aims: There are few data concerning the effects of thyroid disorders on intraocular pressure (IOP), central corneal thickness (CCT) and retinal thickness (RT) and to our knowledge no data have been reported in Hashimoto"s thyroiditis (HT). In this study we aimed to evaluate the alterations in IOP, CCT and RT in patients with euthyroid HT.

Methods: In this cross-sectional study we examined IOP, CCT and RT in patients with euthyroid HT and age and gender matched controls.

Results: We evaluated 80 eyes of 40 patients with euthyroid HT and 96 eyes of 48 controls. Serum sensitive thyroid stimulating hormone (sTSH) (2.10±1.04 vs 1.92±1.23 uIU/ml), free triiodothyronine (fT3) (3.19±0.43 vs 3.14±0.34 pg/ml), and free tetraiodothyronine (fT4) (1.20±0.14 vs 1.18±0.13 ng/dl) levels were similar between the two groups. No statistically significant difference was observed in mean RT (266.93± 26.46 vs 275.35± 38.81 μm), CCT (533.68±29.28 vs 540.06±29.13 μm), or IOP (13.98±2.42 vs 14.32±2.62 mmHg) between HT patients and controls. In the HT group Anti-TPO was negatively correlated with mean RT (r = −0.227, p = 0.033).

Conclusions: We have found no differences in CCT, RT and IOP between euthyroid HT patients and controls. In the present study, however there was a negative correlation between the anti- TPO levels and RT. Keywords : Euthyroid Hashimoto"s thyroiditis, central corneal thickness, retinal thickness, intraocular pressure